Screening of Phenanthroquinolizidine Alkaloid Derivatives for Inducing Cell Death of L1210 Leukemia Cells with Negative and Positive P-glycoprotein Expression

We describe the screening of a set of cryptopleurine derivatives, namely thienoquinolizidine derivatives and (epi-)benzo analogs with bioactive phenanthroquinolizidine alkaloids that induce cytotoxic effects in the mouse lymphocytic leukemia cell line L1210. We used three variants of L1210 cells: i)...

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Published in:Molecules
Main Authors: Kubíčková, Jana, Elefantová, Katarína, Pavlikova, Lucia, Cagala, Martin, Šereš, Mário, Šafář, Peter, Marchalín, Štefan, Ďurišová, Kamila, Boháčová, Viera, Sulova, Zdena, Lakatoš, Boris, Breier, Albert, Olejníková, Petra
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600356/
https://ncbi.nlm.nih.gov/pubmed/31195716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24112127
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