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Single-Cell Virus Sequencing of Influenza Infections That Trigger Innate Immunity

Influenza virus-infected cells vary widely in their expression of viral genes and only occasionally activate innate immunity. Here, we develop a new method to assess how the genetic variation in viral populations contributes to this heterogeneity. We do this by determining the transcriptome and full...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Russell, Alistair B., Elshina, Elizaveta, Kowalsky, Jacob R., te Velthuis, Aartjan J. W., Bloom, Jesse D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600203/
https://ncbi.nlm.nih.gov/pubmed/31068418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00500-19
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