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N(ɛ)-acetyl lysine derivatives with zinc binding groups as novel HDAC inhibitors
HDAC inhibitors have been developed very rapidly in clinical trials and even in approvals for treating several cancers. However, there are few reported HDAC inhibitors designed from N(ɛ)-acetyl lysine. In the current study, we raised a novel design, which concerns N(ɛ)-acetyl lysine derivatives cont...
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| Publicado no: | R Soc Open Sci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6599804/ https://ncbi.nlm.nih.gov/pubmed/31312496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.190338 |
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