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Withaferin A-mediated apoptosis in breast cancer cells is associated with alterations in mitochondrial dynamics

Withaferin A (WA), a steroidal lactone derived from a medicinal plant (Withania somnifera), inhibits cancer development in transgenic and chemically-induced rodent models of breast cancer but the underlying mechanism is not fully grasped. We have shown previously that WA treatment causes apoptotic c...

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Detalhes bibliográficos
Publicado no:Mitochondrion
Main Authors: Sehrawat, Anuradha, Samanta, Suman K., Hahm, Eun-Ryeong, St. Croix, Claudette, Watkins, Simon, Singh, Shivendra V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599725/
https://ncbi.nlm.nih.gov/pubmed/30685490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2019.01.003
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