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Nuclear envelope assembly defects link mitotic errors to chromothripsis
Defects in the architecture or integrity of the nuclear envelope (NE) are associated with a variety of human diseases(1). Micronuclei, one common nuclear aberration, are an origin for chromothripsis(2), a catastrophic mutational process commonly observed in cancer(3–5). Chromothripsis occurs after m...
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| Publicado no: | Nature |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6599625/ https://ncbi.nlm.nih.gov/pubmed/30232450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0534-z |
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