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Chiral aminophosphines derived from hydroxyproline and their application in allene–imine [4 + 2] annulation
A robust synthetic route from l-hydroxyproline (l-Hyp) to phosphines has established an expandable library of six chiral aminophosphines, which were then applied to the phosphine-catalyzed [4 + 2] allene–imine annulation. The enantioinduction in the annulations—induced by a purely steric effect—were...
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| Vydáno v: | J Antibiot (Tokyo) |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6599608/ https://ncbi.nlm.nih.gov/pubmed/30940911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41429-019-0181-0 |
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