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Synthetic studies towards the penicisulfuranols: Synthesis of an advanced spirocyclic diketopiperazine intermediate

The 2,5-diketopiperazine (DKP) moiety is a core feature of many natural products and medicinally relevant scaffolds. As part of our efforts directed towards a total synthesis of penicisulfuranol B, we have developed and report herein: (1) the preparation of an N-hydroxy diketopiperazine intermediate...

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Publicat a:Tetrahedron
Autors principals: Gayler, Kevin M., Lambert, Kyle M., Wood, John L.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599588/
https://ncbi.nlm.nih.gov/pubmed/31258206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2019.01.032
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