Epigenetic Priming of Human Pluripotent Stem Cell-derived Cardiac Progenitor Cells Accelerates Cardiomyocyte Maturation

[Image: see text] Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) exhibit a fetal phenotype that limits in vitro and therapeutic applications. Strategies to promote cardiomyocyte maturation have focused interventions on differentiated hPSC-CMs, but this study tests priming of early car...

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Bibliografski detalji
Izdano u:Stem Cells
Glavni autori: Biermann, Mitch, Cai, Wenxuan, Lang, Di, Hermsen, Jack, Profio, Luke, Zhou, Ying, Czirok, Andras, Isai, Dona G., Napiwocki, Brett N., Rodriguez, Adriana M., Brown, Matthew E, Woon, Marites T., Shao, Annie, Han, Tianxiao, Park, Donglim, Hacker, Timothy A., Crone, Wendy C., Burlingham, William J, Glukhov, Alexey V., Ge, Ying, Kamp, Timothy J.
Format: Artigo
Jezik:Inglês
Izdano: 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599574/
https://ncbi.nlm.nih.gov/pubmed/31087611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3021
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