Epigenetic Priming of Human Pluripotent Stem Cell-derived Cardiac Progenitor Cells Accelerates Cardiomyocyte Maturation

[Image: see text] Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) exhibit a fetal phenotype that limits in vitro and therapeutic applications. Strategies to promote cardiomyocyte maturation have focused interventions on differentiated hPSC-CMs, but this study tests priming of early car...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Biermann, Mitch, Cai, Wenxuan, Lang, Di, Hermsen, Jack, Profio, Luke, Zhou, Ying, Czirok, Andras, Isai, Dona G., Napiwocki, Brett N., Rodriguez, Adriana M., Brown, Matthew E, Woon, Marites T., Shao, Annie, Han, Tianxiao, Park, Donglim, Hacker, Timothy A., Crone, Wendy C., Burlingham, William J, Glukhov, Alexey V., Ge, Ying, Kamp, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599574/
https://ncbi.nlm.nih.gov/pubmed/31087611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3021
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