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LADL: Light-activated dynamic looping for endogenous gene expression control

Mammalian genomes are folded into tens of thousands of long-range looping interactions. The cause and effect relationship between looping and genome function is poorly understood, and the extent to which loops are dynamic on short time scales remains an unanswered question. Here we engineer a new cl...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Kim, Ji Hun, Rege, Mayuri, Valeri, Jacqueline, Dunagin, Margaret C., Metzger, Aryeh, Titus, Katelyn R., Gilgenast, Thomas G., Gong, Wanfeng, Beagan, Jonathan A., Raj, Arjun, Phillips-Cremins, Jennifer E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599567/
https://ncbi.nlm.nih.gov/pubmed/31235883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0436-5
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