Persistently Elevated Glucagon-Like Peptide 1 Levels Among Critically-Ill Surgical Patients After Sepsis and Development of Chronic Critical Illness and Dismal Long-Term Outcomes

BACKGROUND: Glucagon-like peptide-1 (GLP-1) is a gut derived incretin hormone that stimulates insulin secretion, cellular glucose uptake and has immune-regulatory functions. GLP-1 is markedly altered following trauma and sepsis, but the implications remain unclear. STUDY DESIGN: We performed an anal...

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Veröffentlicht in:J Am Coll Surg
Hauptverfasser: Brakenridge, Scott C, Moore, Frederick A, Mercier, Nicole R, Cox, Michael, Wu, Quron, Moldawer, Lyle L, Mohr, Alicia M, Efron, Philip A, Smith, R Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599553/
https://ncbi.nlm.nih.gov/pubmed/30991107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2019.04.014
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