Maternal Western-style diet affects offspring islet composition and function in a non-human primate model of maternal over-nutrition

OBJECTIVE: In humans, offspring of women who are overweight or obese are more likely to develop metabolic disease later in life. Studies in lower animal species reveal that a calorically-dense maternal diet is associated with alterations in islet cell mass and function. The long-term effects of mate...

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Udgivet i:Mol Metab
Main Authors: Elsakr, Joseph M., Dunn, Jennifer C., Tennant, Katherine, Zhao, Sifang Kathy, Kroeten, Karly, Pasek, Raymond C., Takahashi, Diana L., Dean, Tyler A., Velez Edwards, Digna R., McCurdy, Carrie E., Aagaard, Kjersti M., Powers, Alvin C., Friedman, Jacob E., Kievit, Paul, Gannon, Maureen
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599455/
https://ncbi.nlm.nih.gov/pubmed/31036449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.03.010
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