Maternal Western-style diet affects offspring islet composition and function in a non-human primate model of maternal over-nutrition

OBJECTIVE: In humans, offspring of women who are overweight or obese are more likely to develop metabolic disease later in life. Studies in lower animal species reveal that a calorically-dense maternal diet is associated with alterations in islet cell mass and function. The long-term effects of mate...

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Pubblicato in:Mol Metab
Autori principali: Elsakr, Joseph M., Dunn, Jennifer C., Tennant, Katherine, Zhao, Sifang Kathy, Kroeten, Karly, Pasek, Raymond C., Takahashi, Diana L., Dean, Tyler A., Velez Edwards, Digna R., McCurdy, Carrie E., Aagaard, Kjersti M., Powers, Alvin C., Friedman, Jacob E., Kievit, Paul, Gannon, Maureen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599455/
https://ncbi.nlm.nih.gov/pubmed/31036449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.03.010
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