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Screening of caspase-3 inhibitors from natural molecule database using e-pharmacophore and docking studies

Caspase a protease family member, have a vital role in cell death and inflammation process. Caspase-3, an effector caspase controls the regulation of apoptosis and has an anti apoptotic function. The mechanical significance of restoring apoptosis signaling to selectively target malignant cells is ut...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioinformation
Prif Awduron: Eda, Sasidhar Reddy, Veeramachaneni, Ganesh Kumar, Bondili, Jayakumar Singh, Jinka, Rajeswari
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Biomedical Informatics 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599438/
https://ncbi.nlm.nih.gov/pubmed/31285640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630015240
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