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Reconstitution and Characterization of BCL-2 Family Proteins in Lipid Bilayer Nanodiscs

The BCL-2 family proteins are key regulators of programmed cell death or apoptosis, and represent important targets for the development of anticancer drugs. Because their functions are intimately connected with intracellular membranes, it is important to perform structural and activity studies in pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Methods Mol Biol
Hauptverfasser: Yao, Yong, Marassi, Francesca M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599400/
https://ncbi.nlm.nih.gov/pubmed/30536010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-8861-7_16
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