Reconstitution and NMR Characterization of the Ion-Channel Accessory Subunit Barttin in Detergents and Lipid-Bilayer Nanodiscs

Barttin is an accessory subunit of ClC-K chloride channels expressed in the kidney and the inner ear. Main functions of ClC-K/barttin channels are the generation of the cortico-medullary osmotic gradients in the kidney and the endocochlear potential in the inner ear. Mutations in the gene encoding b...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Viennet, Thibault, Bungert-Plümke, Stefanie, Elter, Shantha, Viegas, Aldino, Fahlke, Christoph, Etzkorn, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6427064/
https://ncbi.nlm.nih.gov/pubmed/30931313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00013
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