miR-23b and miR-27b are oncogenic microRNAs in breast cancer: evidence from a CRISPR/Cas9 deletion study

BACKGROUND: Altered expression of microRNAs (miRNAs) is known to contribute to cancer progression. miR-23b and miR-27b, encoded within the same miRNA cluster, are reported to have both tumor suppressive and oncogenic activity across human cancers, including breast cancer. METHODS: To clarify this di...

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Vydáno v:BMC Cancer
Hlavní autoři: Hannafon, Bethany N., Cai, Angela, Calloway, Cameron L., Xu, Yi-Fan, Zhang, Roy, Fung, Kar-Ming, Ding, Wei-Qun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599331/
https://ncbi.nlm.nih.gov/pubmed/31253120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5839-2
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