Optimal composition and position of histidine-containing tags improves biodistribution of (99m)Tc-labeled DARPin G3

Radionuclide molecular imaging of HER2 expression in disseminated cancer enables stratification of patients for HER2-targeted therapies. DARPin G3, a small (14 kDa) engineered scaffold protein, is a promising probe for imaging of HER2. We hypothesized that position (C- or N-terminus) and composition...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vorobyeva, Anzhelika, Schulga, Alexey, Konovalova, Elena, Güler, Rezan, Löfblom, John, Sandström, Mattias, Garousi, Javad, Chernov, Vladimir, Bragina, Olga, Orlova, Anna, Tolmachev, Vladimir, Deyev, Sergey M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599047/
https://ncbi.nlm.nih.gov/pubmed/31253840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45795-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados