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On the prevention of kidney uptake of radiolabeled DARPins
BACKGROUND: Designed ankyrin repeat proteins (DARPins) are small engineered scaffold proteins (14–18 kDa) that demonstrated promising tumor-targeting properties in preclinical studies. However, high renal accumulation of activity for DARPins labeled with residualizing labels is a limitation for targ...
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| Publicado no: | EJNMMI Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7000568/ https://ncbi.nlm.nih.gov/pubmed/32020413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-020-0599-1 |
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