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DNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci
DNA double strand breaks (DSBs) pose a high risk for genome integrity. Cells repair DSBs through homologous recombination (HR) when a sister chromatid is available. HR is upregulated by the cycling dependent kinase (CDK) despite the paradox of telophase, where CDK is high but a sister chromatid is n...
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| Vydáno v: | Nat Commun |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6598993/ https://ncbi.nlm.nih.gov/pubmed/31253793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10742-8 |
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