Optimization of whole-cell biotransformation for scale-up production of α-arbutin from hydroquinone by the use of recombinant Escherichia coli

α-Arbutin is an effective skin-whitening cosmetic ingredient and hyperpigmentation therapy agent. It can be synthesized by one-step enzymatic glycosylation of hydroquinone (HQ), but limited by the low yield. Amylosucrase (Amy-1) from Xanthomonas campestris pv. campestris 8004 was recently identified...

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Bibliografiske detaljer
Udgivet i:AMB Express
Main Authors: Zhu, Linjiang, Xu, Min, Lu, Changxin, Chen, Luyi, Xu, Anjie, Fang, Jingyi, Chen, Hanchi, Lu, Yuele, Fan, Yongxian, Chen, Xiaolong
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2019
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598918/
https://ncbi.nlm.nih.gov/pubmed/31254161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-019-0820-7
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