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Attenuated phenotypes and analysis of a herpes simplex virus 1 strain with partial deletion of the UL7, UL41 and LAT genes

We previously constructed a herpes simplex virus 1 (HSV-1) UL7 mutant virus (M1) and showed that a partial deletion mutation of the UL7 gene led to a lower proliferative rate and an attenuated phenotype. Using the M1 mutant, we further modified the UL41 gene, which encodes another tegument protein,...

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Detalhes bibliográficos
Publicado no:Virol Sin
Main Authors: Xu, Xingli, Guo, Yingqiu, Fan, Shengtao, Cui, Pingfang, Feng, Min, Wang, Lichun, Zhang, Ying, Liao, Yun, Zhang, Xiaolong, Li, Qihan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598894/
https://ncbi.nlm.nih.gov/pubmed/28971351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-017-3947-1
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