Pharmacokinetic and Pharmacodynamic Integration and Resistance Analysis of Tilmicosin Against Mycoplasma gallisepticum in an In Vitro Dynamic Model

Mycoplasma gallisepticum is the major pathogen causing chronic respiratory disease in chickens. In the present study, we successfully established a one-compartment open model with first-order absorption to determine the relationship between tilmicosin pharmacokinetic and pharmacodynamic (PK/PD) indi...

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Vydáno v:Front Pharmacol
Hlavní autoři: Huang, Zilong, Wu, Yuzhi, Zhou, Zichong, Xia, Xirui, Gu, Xiaoyan, Cai, Qinren, Shen, Xiangguang, Yang, Hong, Ding, Huanzhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598723/
https://ncbi.nlm.nih.gov/pubmed/31293418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00670
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