Pharmacokinetic and Pharmacodynamic Integration and Resistance Analysis of Tilmicosin Against Mycoplasma gallisepticum in an In Vitro Dynamic Model

Mycoplasma gallisepticum is the major pathogen causing chronic respiratory disease in chickens. In the present study, we successfully established a one-compartment open model with first-order absorption to determine the relationship between tilmicosin pharmacokinetic and pharmacodynamic (PK/PD) indi...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Huang, Zilong, Wu, Yuzhi, Zhou, Zichong, Xia, Xirui, Gu, Xiaoyan, Cai, Qinren, Shen, Xiangguang, Yang, Hong, Ding, Huanzhong
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598723/
https://ncbi.nlm.nih.gov/pubmed/31293418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00670
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