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Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
Bioorthogonal tools enable cell-type-specific proteomics, a prerequisite to understanding biological processes in multicellular organisms. Here we report two engineered aminoacyl-tRNA synthetases for mammalian bioorthogonal labeling: a tyrosyl (ScTyr(Y43G)) and a phenylalanyl (MmPhe(T413G)) tRNA syn...
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| 出版年: | J Am Chem Soc |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6598694/ https://ncbi.nlm.nih.gov/pubmed/29775058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b03074 |
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