Cetuximab combined with induction oxaliplatin and capecitabine, followed by neoadjuvant chemoradiation for locally advanced rectal cancer: SWOG 0713

BACKGROUND: Neoadjuvant chemoradiation (NCRT) is standard treatment for locally advanced rectal cancer. Pathologic complete response (pCR) has associated with improved survival. In modern phase III trials of NCRT, pCR ranges from 10–20%. Cetuximab improves response in KRAS wild-type (KRAS-wt) metast...

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Udgivet i:Clin Colorectal Cancer
Main Authors: Leichman, Cynthia Gail, McDonough, Shannon L., Smalley, Stephen R., Billingsley, Kevin G., Lenz, Heinz-Josef, Beldner, Matthew A., Hezel, Aram F., Velasco, Mario R., Guthrie, Katherine A., Blanke, Charles D., Hochster, Howard S.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598683/
https://ncbi.nlm.nih.gov/pubmed/29233486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clcc.2017.10.008
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