Higher capecitabine AUC in elderly patients with advanced colorectal cancer (SWOGS0030)

BACKGROUND: The aging process is accompanied by physiological changes including reduced glomerular filtration and hepatic function, as well as changes in gastric secretions. To investigate what effect would aging have on the disposition of capecitabine and its metabolites, the pharmacokinetics betwe...

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Dades bibliogràfiques
Autors principals: Louie, S G, Ely, B, Lenz, H-J, Albain, K S, Gotay, C, Coleman, D, Raghavan, D, Shields, A F, Gold, P J, Blanke, C D
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
Matèries:
Clinical Study
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790171/
https://ncbi.nlm.nih.gov/pubmed/24022189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.517
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