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Higher capecitabine AUC in elderly patients with advanced colorectal cancer (SWOGS0030)
BACKGROUND: The aging process is accompanied by physiological changes including reduced glomerular filtration and hepatic function, as well as changes in gastric secretions. To investigate what effect would aging have on the disposition of capecitabine and its metabolites, the pharmacokinetics betwe...
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| Κύριοι συγγραφείς: | , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3790171/ https://ncbi.nlm.nih.gov/pubmed/24022189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.517 |
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