Fluoxetine and Vortioxetine Reverse Depressive-Like Phenotype and Memory Deficits Induced by Aβ(1-42) Oligomers in Mice: A Key Role of Transforming Growth Factor-β1

Depression is a risk factor for the development of Alzheimer’s disease (AD), and the presence of depressive symptoms significantly increases the conversion of mild cognitive impairment (MCI) into AD. A long-term treatment with antidepressants reduces the risk to develop AD, and different second-gene...

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Udgivet i:Front Pharmacol
Main Authors: Torrisi, Sebastiano Alfio, Geraci, Federica, Tropea, Maria Rosaria, Grasso, Margherita, Caruso, Giuseppe, Fidilio, Annamaria, Musso, Nicolò, Sanfilippo, Giulia, Tascedda, Fabio, Palmeri, Agostino, Salomone, Salvatore, Drago, Filippo, Puzzo, Daniela, Leggio, Gian Marco, Caraci, Filippo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598642/
https://ncbi.nlm.nih.gov/pubmed/31293421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00693
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