Buspirone Counteracts MK-801-Induced Schizophrenia-Like Phenotypes through Dopamine D(3) Receptor Blockade

Background: Several efforts have been made to develop effective antipsychotic drugs. Currently, available antipsychotics are effective on positive symptoms, less on negative symptoms, but not on cognitive impairment, a clinically relevant dimension of schizophrenia. Drug repurposing offers great adv...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Torrisi, Sebastiano Alfio, Salomone, Salvatore, Geraci, Federica, Caraci, Filippo, Bucolo, Claudio, Drago, Filippo, Leggio, Gian Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632784/
https://ncbi.nlm.nih.gov/pubmed/29046641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00710
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