Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani

Chagas disease and leishmaniasis are neglected tropical disorders caused by the protozoans Trypanosoma cruzi and Leishmania spp. Carbonic anhydrases (CAs, EC 4.2.1.1) from these protozoans (α-TcCA and β-LdcCA) have been validated as promising targets for chemotherapic interventions. Many anti-protoz...

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Veröffentlicht in:J Enzyme Inhib Med Chem
Hauptverfasser: Nocentini, Alessio, Osman, Sameh M., Rodrigues, Igor A., Cardoso, Veronica S., Alasmary, Fatmah Ali S., AlOthman, Zeid, Vermelho, Alane B., Gratteri, Paola, Supuran, Claudiu T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
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Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598531/
https://ncbi.nlm.nih.gov/pubmed/31219348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1626375
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