Effects of GRM4, SCN2A and SCN3B polymorphisms on antiepileptic drugs responsiveness and epilepsy susceptibility

BACKGROUND: Pharmacotherapy of epilepsy including antiepileptic drugs (AEDs) is one of the main treatment approaches. As a biological target, sodium channels (Nav channels) and glutamate receptor genes are playing a major role in the etiology and treatment of epilepsy. OBJECTIVE: This study aims to...

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Vydáno v:Saudi Pharm J
Hlavní autoři: AL-Eitan, Laith N., Al-Dalalah, Islam M., Aljamal, Hanan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598501/
https://ncbi.nlm.nih.gov/pubmed/31297029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2019.04.009
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