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Ni-Catalyzed Enantioselective Conjunctive Coupling with C(sp(3)) Electrophiles: A Radical-Ionic Mechanistic Dichotomy

The catalytic enantioselective conjunctive coupling of C(sp(3)) electrophiles can be accomplished with Ni catalysis. The enantioselectivity of the reaction is dependent on reaction mechanism with many substrates able to engage in an asymmetric process with Pybox-Ni complexes, whereas other substrate...

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Pubblicato in:J Am Chem Soc
Autori principali: Lovinger, Gabriel J., Morken, James P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598435/
https://ncbi.nlm.nih.gov/pubmed/29116784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b10519
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