Medial Temporal Lobe Disconnection and Hyperexcitability Across Alzheimer’s Disease Stages

 The posteromedial cortex (PMC) and medial temporal lobes (MTL) are two brain regions particularly vulnerable in Alzheimer’s disease (AD). We have reviewed the spatiotemporal patterns of amyloid-β and tau accumulation, local MTL functional alterations and MTL-PMC network reconfiguration, and propose...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis Rep
Main Authors: Pasquini, Lorenzo, Rahmani, Farzaneh, Maleki-Balajoo, Somayeh, La Joie, Renaud, Zarei, Mojtaba, Sorg, Christian, Drzezga, Alexander, Tahmasian, Masoud
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597961/
https://ncbi.nlm.nih.gov/pubmed/31259307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-190121
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