Medial Temporal Lobe Disconnection and Hyperexcitability Across Alzheimer’s Disease Stages

 The posteromedial cortex (PMC) and medial temporal lobes (MTL) are two brain regions particularly vulnerable in Alzheimer’s disease (AD). We have reviewed the spatiotemporal patterns of amyloid-β and tau accumulation, local MTL functional alterations and MTL-PMC network reconfiguration, and propose...

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Publicat a:J Alzheimers Dis Rep
Autors principals: Pasquini, Lorenzo, Rahmani, Farzaneh, Maleki-Balajoo, Somayeh, La Joie, Renaud, Zarei, Mojtaba, Sorg, Christian, Drzezga, Alexander, Tahmasian, Masoud
Format: Artigo
Idioma:Inglês
Publicat: IOS Press 2019
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597961/
https://ncbi.nlm.nih.gov/pubmed/31259307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-190121
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