EWSR1-FLI1 Activation of the Cancer/Testis Antigen FATE1 Promotes Ewing Sarcoma Survival

Ewing sarcoma is characterized by a pathognomonic chromosomal translocation that generates the EWSR1-FLI1 chimeric transcription factor. The transcriptional targets of EWSR1-FLI1 that are essential for tumorigenicity are incompletely defined. Here, we found that EWSR1-FLI1 modulates the expression o...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Gallegos, Zachary R., Taus, Patrick, Gibbs, Zane A., McGlynn, Kathleen, Gomez, Nicholas C., Davis, Ian, Whitehurst, Angelique W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597881/
https://ncbi.nlm.nih.gov/pubmed/31036566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00138-19
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