An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogenesis

The presence of the chimeric EWSR1-FLI1 oncoprotein is the main and initiating event defining Ewing sarcoma (ES). The dysregulation of epigenomic and proteomic homeostasis induced by the oncoprotein contributes to a wide variety of events involved in oncogenesis and tumor progression. Attempts at st...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: García-Domínguez, Daniel J., Hontecillas-Prieto, Lourdes, León, Eduardo Andrés, Sánchez-Molina, Sara, Rodríguez-Núñez, Pablo, Morón, Francisco J., Hajji, Nabil, Mackintosh, Carlos, de Álava, Enrique
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274397/
https://ncbi.nlm.nih.gov/pubmed/32502203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234243
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