Genome-wide CRISPR-based gene knockout screens reveal cellular factors and pathways essential for nasopharyngeal carcinoma

Early diagnosis of nasopharyngeal carcinoma (NPC) is difficult because of a lack of specific symptoms. Many patients have advanced disease at diagnosis, and these patients respond poorly to treatment. New treatments are therefore needed to improve the outcome of NPC. To better understand the molecul...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wang, Chong, Jiang, Sizun, Ke, Liangru, Zhang, Luyao, Li, Difei, Liang, Jun, Narita, Yohei, Hou, Isabella, Chen, Chen-hao, Wang, Liangwei, Zhong, Qian, Ling, Yihong, Lv, Xing, Xiang, Yanqun, Guo, Xiang, Teng, Mingxiang, Tsao, Sai-Wah, Gewurz, Benjamin E., Zeng, Mu-Sheng, Zhao, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597810/
https://ncbi.nlm.nih.gov/pubmed/31073033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008793
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