Genome-wide CRISPR-based gene knockout screens reveal cellular factors and pathways essential for nasopharyngeal carcinoma

Early diagnosis of nasopharyngeal carcinoma (NPC) is difficult because of a lack of specific symptoms. Many patients have advanced disease at diagnosis, and these patients respond poorly to treatment. New treatments are therefore needed to improve the outcome of NPC. To better understand the molecul...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Wang, Chong, Jiang, Sizun, Ke, Liangru, Zhang, Luyao, Li, Difei, Liang, Jun, Narita, Yohei, Hou, Isabella, Chen, Chen-hao, Wang, Liangwei, Zhong, Qian, Ling, Yihong, Lv, Xing, Xiang, Yanqun, Guo, Xiang, Teng, Mingxiang, Tsao, Sai-Wah, Gewurz, Benjamin E., Zeng, Mu-Sheng, Zhao, Bo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597810/
https://ncbi.nlm.nih.gov/pubmed/31073033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008793
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