Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M

The fibrogenic response in tissue-resident fibroblasts is determined by the balance between activation and repression signals from the tissue microenvironment. While the molecular pathways by which transforming growth factor-1 (TGF-β1) activates pro-fibrogenic mechanisms have been extensively studie...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Abe, Hajime, Takeda, Norihiko, Isagawa, Takayuki, Semba, Hiroaki, Nishimura, Satoshi, Morioka, Masaki Suimye, Nakagama, Yu, Sato, Tatsuyuki, Soma, Katsura, Koyama, Katsuhiro, Wake, Masaki, Katoh, Manami, Asagiri, Masataka, Neugent, Michael L., Kim, Jung-whan, Stockmann, Christian, Yonezawa, Tomo, Inuzuka, Ryo, Hirota, Yasushi, Maemura, Koji, Yamashita, Takeshi, Otsu, Kinya, Manabe, Ichiro, Nagai, Ryozo, Komuro, Issei
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597788/
https://ncbi.nlm.nih.gov/pubmed/31249305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10859-w
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