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The Relationship Between Circulating Acetaminophen-Protein Adduct Concentrations and Alanine Aminotransferase Activities in Patients With and Without Acetaminophen Overdose and Toxicity

INTRODUCTION: Measurement of serum acetaminophen-protein adducts (APAP-CYS) has been suggested to support or refute a diagnosis of acetaminophen (APAP)-induced hepatotoxicity when ingestion histories are unreliable or unavailable and when circulating APAP concentrations are low or undetectable. Non-...

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Detalhes bibliográficos
Publicado no:J Med Toxicol
Main Authors: Curry, Steven C., Padilla-Jones, Angela, Ruha, Anne-Michelle, O’Connor, Ayrn D., Kang, A Min, Wilkins, Diana G., Jaeschke, Hartmut, Wilhelms, Kelly, Gerkin, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597749/
https://ncbi.nlm.nih.gov/pubmed/30980348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13181-019-00705-2
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