Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes

Sufficient vascular supply is indispensable for brain development and function, whereas dysfunctional blood vessels are associated with human diseases such as vascular malformations, stroke or neurodegeneration. Pericytes are capillary-associated mesenchymal cells that limit vascular permeability an...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Diéguez-Hurtado, Rodrigo, Kato, Katsuhiro, Giaimo, Benedetto Daniele, Nieminen-Kelhä, Melina, Arf, Hendrik, Ferrante, Francesca, Bartkuhn, Marek, Zimmermann, Tobias, Bixel, M. Gabriele, Eilken, Hanna M., Adams, Susanne, Borggrefe, Tilman, Vajkoczy, Peter, Adams, Ralf H.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597568/
https://ncbi.nlm.nih.gov/pubmed/31249304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10643-w
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