Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes

Sufficient vascular supply is indispensable for brain development and function, whereas dysfunctional blood vessels are associated with human diseases such as vascular malformations, stroke or neurodegeneration. Pericytes are capillary-associated mesenchymal cells that limit vascular permeability an...

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Vydáno v:Nat Commun
Hlavní autoři: Diéguez-Hurtado, Rodrigo, Kato, Katsuhiro, Giaimo, Benedetto Daniele, Nieminen-Kelhä, Melina, Arf, Hendrik, Ferrante, Francesca, Bartkuhn, Marek, Zimmermann, Tobias, Bixel, M. Gabriele, Eilken, Hanna M., Adams, Susanne, Borggrefe, Tilman, Vajkoczy, Peter, Adams, Ralf H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597568/
https://ncbi.nlm.nih.gov/pubmed/31249304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10643-w
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