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Active Site Labeling of Fatty Acid and Polyketide Acyl-Carrier Protein Transacylases

Metabolic engineering of fatty acids and polyketides remains challenging due to unresolved protein-protein interactions that are essential to synthase activity. While several chemical probes have been developed to capture and visualize protein interfaces in these systems, acyl carrier protein (ACP)...

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Vydáno v:Org Biomol Chem
Hlavní autoři: Davis, Tony D., Michaud, Jennifer M., Burkart, Michael D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597490/
https://ncbi.nlm.nih.gov/pubmed/31044196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob03229g
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