Central nervous system regeneration is driven by microglia necroptosis and repopulation

Failed regeneration of central nervous system myelin contributes to clinical decline in neuroinflammatory and neurodegenerative diseases, for which there is an unmet therapeutic need. Here, we reveal that efficient remyelination requires death of pro-inflammatory microglia followed by repopulation t...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Lloyd, Amy F., Davies, Claire L., Holloway, Rebecca K., Labrak, Yasmine, Ireland, Graeme, Carradori, Dario, Dillenburg, Alessandra, Borger, Eva, Soong, Daniel, Richardson, Jill C., Kuhlmann, Tanja, Williams, Anna, Pollard, Jeffrey W., des Rieux, Anne, Priller, Josef, Miron, Veronique E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597360/
https://ncbi.nlm.nih.gov/pubmed/31182869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-019-0418-z
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