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Identification and Characterization of Two Novel Oncogenic mTOR Mutations

Mammalian target of rapamycin (mTOR) signaling is often aberrantly activated, particularly when genetically activated, in human cancers. mTOR inhibitors targeting the activated mTOR signaling are highly promising anti-cancer drugs. Knowing the activating genetic change in mTOR can help guide the use...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Murugan, Avaniyapuram Kannan, Liu, Rengyun, Xing, Mingzhao
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597304/
https://ncbi.nlm.nih.gov/pubmed/30918329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0787-5
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