FDPS cooperates with PTEN loss to promote prostate cancer progression through modulation of small GTPases/AKT axis

Farnesyl Diphosphate Synthase (FDPS), a mevalonate pathway enzyme, is highly expressed in several cancers, including prostate cancer (PCa). To date, the mechanistic, functional and clinical significance of FDPS in cancer remains unexplored. We evaluated the FDPS expression and its cancer-associated...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Seshacharyulu, Parthasarathy, Rachagani, Satyanarayana, Muniyan, Sakthivel, Siddiqui, Jawed A., Cruz, Eric, Sharma, Sunandini, Krishnan, Ramakrishnan, Killips, Brigham J., Sheinin, Yuri, Lele, Subodh M., Smith, Lynette M., Talmon, Geoffrey A., Ponnusamy, Moorthy P., Datta, Kaustubh, Batra, Surinder K
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597298/
https://ncbi.nlm.nih.gov/pubmed/30914801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0791-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados