FDPS cooperates with PTEN loss to promote prostate cancer progression through modulation of small GTPases/AKT axis

Farnesyl Diphosphate Synthase (FDPS), a mevalonate pathway enzyme, is highly expressed in several cancers, including prostate cancer (PCa). To date, the mechanistic, functional and clinical significance of FDPS in cancer remains unexplored. We evaluated the FDPS expression and its cancer-associated...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Seshacharyulu, Parthasarathy, Rachagani, Satyanarayana, Muniyan, Sakthivel, Siddiqui, Jawed A., Cruz, Eric, Sharma, Sunandini, Krishnan, Ramakrishnan, Killips, Brigham J., Sheinin, Yuri, Lele, Subodh M., Smith, Lynette M., Talmon, Geoffrey A., Ponnusamy, Moorthy P., Datta, Kaustubh, Batra, Surinder K
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597298/
https://ncbi.nlm.nih.gov/pubmed/30914801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0791-9
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires