Overexpression of PD2 leads to increased tumorigenicity and metastasis in pancreatic ductal adenocarcinoma

Pancreatic differentiation 2 (PD2), an important subunit of the human PAF complex, was identified after differential screening analysis of 19q13 amplicon, and its overexpression induces oncogenic transformation of NIH3T3 cells, hence raising the possibility of a role for PD2 in tumorigenesis and met...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Vaz, Arokia Priyanka, Deb, Shonali, Rachagani, Satyanarayana, Dey, Parama, Muniyan, Sakthivel, Lakshmanan, Imayavaramban, Karmakar, Saswati, Smith, Lynette, Johansson, Sonny, Lele, Subodh, Ouellette, Michel, Ponnusamy, Moorthy P., Batra, Surinder K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823108/
https://ncbi.nlm.nih.gov/pubmed/26689992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6580
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