Genetic Variants Associated with Immunosuppressant Pharmacokinetics and Adverse Effects in the DeKAF Genomics Genome Wide Association Studies.

BACKGROUND: The immunosuppressants tacrolimus and mycophenolate are important components to the success of organ transplantation, but are also associated with adverse effects such as nephrotoxicity, anemia, leukopenia and new onset diabetes after transplant (NODAT). In this report, we attempted to i...

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Publicado no:Transplantation
Main Authors: Oetting, William S., Wu, Baolin, Schladt, David P., Guan, Weihua, van Setten, Jessica, Keating, Brendan J., Iklé, David, Remmel, Rory P., Dorr, Casey R., Mannon, Roslyn B., Matas, Arthur J., Israni, Ajay K., Jacobson, Pamala A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597284/
https://ncbi.nlm.nih.gov/pubmed/30801552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000002625
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