Endoplasmic Reticulum Stress Promotes Liver Cancer Cells to Release Exosomal miR-23a-3p and Up-regulate PD-L1 Expression in Macrophages

Endoplasmic reticulum (ER) stress promotes tumor cell escape from immunosurveillance. However, the underlying mechanisms remain unknown. We hypothesized that ER stress induces hepatocellular carcinoma (HCC) cells to release exosomes, which attenuate antitumor immunity by modulating the expression of...

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Bibliografiske detaljer
Udgivet i:Hepatology
Main Authors: Liu, Jiatao, Fan, Lulu, Yu, Hanqing, Zhang, Ju, He, Yong, Feng, Dechun, Wang, Fang, Li, Xiaoqiu, Liu, Qingqing, Li, Yuhuan, Guo, Zhenli, Gao, Bin, Wei, Wei, Wang, Hua, Sun, Guoping
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597282/
https://ncbi.nlm.nih.gov/pubmed/30854665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30607
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