Endoplasmic Reticulum Stress Promotes Liver Cancer Cells to Release Exosomal miR-23a-3p and Up-regulate PD-L1 Expression in Macrophages

Endoplasmic reticulum (ER) stress promotes tumor cell escape from immunosurveillance. However, the underlying mechanisms remain unknown. We hypothesized that ER stress induces hepatocellular carcinoma (HCC) cells to release exosomes, which attenuate antitumor immunity by modulating the expression of...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Hepatology
Hlavní autoři: Liu, Jiatao, Fan, Lulu, Yu, Hanqing, Zhang, Ju, He, Yong, Feng, Dechun, Wang, Fang, Li, Xiaoqiu, Liu, Qingqing, Li, Yuhuan, Guo, Zhenli, Gao, Bin, Wei, Wei, Wang, Hua, Sun, Guoping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597282/
https://ncbi.nlm.nih.gov/pubmed/30854665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30607
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky